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THE HEART RISKS OF GETTING HIGH













May 16, 2008 - Heavy marijuana use can boost blood levels of a particular protein, perhaps
raising a person's risk of a heart attack or stroke, U.S. government researchers said on
Tuesday.

Dr. Jean Lud Cadet of the National Institute on Drug Abuse, part of the National Institutes of
Health, said the findings point to another example of long-term harm from marijuana. But
marijuana activists expressed doubt about the findings.

Cadet said a lot of previous research has focused on the effects of marijuana on the brain. His
team looked elsewhere in the body, measuring blood protein levels in 18 long-term, heavy
marijuana users and 24 other people who did not use the drug.

Levels of a protein called apolipoprotein C-III were found to be 30 percent higher in the
marijuana users compared to the others. This protein is involved in the body's metabolism of
triglycerides -- a type of fat found in the blood -- and higher levels cause increased levels of
triglycerides, Cadet added.

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Source: ABC News Online